The bill was approved in the state Senate on April 18, and now goes to Gov. Brian Sandoval for consideration.
If signed into law, Nevada would become the 14th U.S. state, along with the District of Columbia, to provide protections based on gender identity or expression.
State law already prohibits employers from singling out job candidates based on race, religion, sexual orientation and other attributes. But transgender people told lawmakers that they are left out of those categories and suffer higher unemployment than the general population.
Two additional transgender protections bills are still making their way through the Nevada Legislature.
On April 25, the state Senate approved SB331, which would prohibits discrimination against gays and transsexuals in places of public accommodation including hotels, motels and restaurants; and SB368, which would prohibit discrimination in housing and other real property transactions.
Both bills are awaiting action in the Assembly.