Quamar Edwards, 25, was indicted on one count each of aggravated murder, aggravated robbery, murder, felonious assault, having weapons under disability and tampering with evidence in connection with the death of 28-year-old Tiffany Edwards.
The suspect and victim are not related.
Tiffany Edwards was found dead on June 26 by a sanitation worker who found her body on a Cincinnati street.
Investigators said Quamar Edwards solicited the victim for sex, and fatally shot her following an argument.
Police and local news reports had originally identified the victim by her male birth name, but family said she identified as Tiffany, and that she began transitioning at age 14.
Quamar Edwards, who turned himself in to police last week, was being held in the Hamilton County Jail on $500,000 bond.
Tiffany Edwards’ death is the fourth murder of a transgender woman in Ohio in the past 18 months, and the third murder of a young transgender woman of color.