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Danish scientists say they’re close to a breakthrough in finding a cure for HIV

Monday, April 29, 2013

AARHUS, Denmark — Scientists and researchers at Aarhus University Hospital in Denmark say they believe there will be a breakthrough in finding a cure for the human immunodeficiency virus (HIV) “within months.”

Researchers are testing a technique that involves releasing the HIV virus from “reservoirs” it forms inside DNA, bringing it to the surface of the cells. Once it comes to the surface, the body’s natural immune system can kill the virus through being boosted by a “vaccine.”

HIV infection is a condition caused by the human immunodeficiency virus (HIV) — the condition gradually destroys the immune system, which makes it harder for the body to fight infections.

The Telegraph UK reported that the results of the trial tests, where the technique has already been proven to work in laboratory, now has shifted to human trials currently being conducted.

The results of the laboratory tests convinced the Danish Research Council to awarded 12 million Danish Kroner ($2.97 million) to carry out clinical trials on humans.

“I am almost certain that we will be successful in releasing the reservoirs of HIV. The challenge will be getting the patient’s immune system to recognize the virus and destroy it.

This depends on the strength and sensitivity of individual immune systems,” Dr. Ole Sogaard, a senior researcher at the Aarhus University Hospital in Denmark, said.

Sogaard also noted that 15 patients are currently taking part in the human trials, and if those patients respond to positively to the treatment the program will be expanded.

Sogaard cautioned that certain behaviors, such as unprotected sex and sharing needles, remained of paramount importance in the fight against HIV, and that a cure is not the same as a preventative vaccine.

According to the National Institutes For Health in Bethesda, Md., the current regime of medications and treatment make it possible for an HIV-positive patient to live a relatively normal life with few side effects even into old age, but if treatment is stopped then symptoms reappear within two weeks.

The Danish research team is utilizing powerful drugs called Histone deacetylase inhibitors (HDAC), which have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptics and also as treatments for cancers and inflammatory diseases.

The treatment potential was discovered almost by accident when Timothy Brown, an HIV sufferer developed leukemia.

Brown had a bone marrow transplant from a donor with a rare genetic mutation, which made his cells resistant to HIV. Brown, known as “the Berlin patient,” is believed to be the first man to ever be cured of the disease.

His case caused a revolution in research, with two new principal approaches. The first is gene therapy, which is expensive and not easily transferable to gene pools around the world, and aims to make a person’s immune system resistant to the HIV virus. The second being the HDAC inhibitor approach.

Worldwide the number of new infections in adults has become broadly stable for the past 4 years. In 2011, 0.77% of the world’s population or 34 million people were recorded as suffering from HIV, according to the World Health Organization (WHO).

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17 more reader comments:

  1. We have rushed too quickly to celebrations, in the past, over such news. Wake me when it’s proven.

    Posted on Monday, April 29, 2013 at 6:34pm
  2. I call bs

    Posted on Monday, April 29, 2013 at 6:37pm
  3. I pray it comes to be +

    Posted on Monday, April 29, 2013 at 6:37pm
  4. guys guys why would the fda or any doctor ever give out the cure with it gone they would lose so much money because people wouldnt be paying for all the treatments or the pills any more they want the money

    Posted on Monday, April 29, 2013 at 6:39pm
  5. another conspiracy theorist. the FDA does not make money on pills, and do not rule the world. They have no regulatory authority of scientists on the other side of the world. and if a cure is found, the FDA will not be able to suppress that news.

    Posted on Monday, April 29, 2013 at 6:44pm
  6. I agree … so sad that the FDA and big pharma wants more money than the billions they already have. There are 2 pharma lobbyists per congressman in our country. There is something really really wrong with this.

    Posted on Monday, April 29, 2013 at 6:45pm
  7. To find a cure to end AIDS and HIV would be an amazing breakthrough

    Posted on Monday, April 29, 2013 at 7:12pm
  8. America – giving up on the fight for more and better sciences since the inception of todays Republican party…

    Posted on Monday, April 29, 2013 at 7:15pm
  9. Cautious optimism?

    Posted on Monday, April 29, 2013 at 7:18pm
  10. We are less than a decade away from a cure. Leave the conspiracy theories at home. Don’t be ignorant.

    Posted on Monday, April 29, 2013 at 7:31pm
  11. Your stupid is showing.

    Posted on Monday, April 29, 2013 at 7:34pm
  12. interesting but i think that there should be more tests and figure out if health insurance is going to cover this or if someone has to pay out of their pocket and how much it will cost cause everyone s immune system is different i am skeptical about this test but there is nothing wrong with positive thinking and high hopes

    Posted on Monday, April 29, 2013 at 7:34pm
  13. I salute the DANISH! Every single earthlink that suffers such maladie, will benefit and many more that will be born.

    Posted on Monday, April 29, 2013 at 8:17pm
  14. Im not religious but GOD i Hope so, I hope they find a cure to this terrible disease it has claimed so many innocent lives.. PLEASE PLEASE ,

    Posted on Monday, April 29, 2013 at 8:46pm
  15. I sure hope so. I have lost so many, many friends to this terrible disease. Too many died way too soon.

    Posted on Monday, April 29, 2013 at 9:10pm
  16. Megan it is more then stupid showing on them.

    Posted on Tuesday, April 30, 2013 at 4:44am
  17. another fool talking out his butt

    Posted on Tuesday, April 30, 2013 at 4:45am